BDBM50176106 Acetic acid 4-[4-(3-ethyl-4-methyl-phenylamino)-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-butyl ester::CHEMBL370565

SMILES: CCc1cc(Nc2cc(=O)n(CCCCOC(C)=O)c(=O)[nH]2)ccc1C

InChI Key: InChIKey=BIKSHULDCZYIEL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50176106   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA polymerase IIIC (Bacillus subtilis)	BDBM50176106 (Acetic acid 4-[4-(3-ethyl-4-methyl-phenylamino)-2,...) Show SMILES CCc1cc(Nc2cc(=O)n(CCCCOC(C)=O)c(=O)[nH]2)ccc1C Show InChI InChI=1S/C19H25N3O4/c1-4-15-11-16(8-7-13(15)2)20-17-12-18(24)22(19(25)21-17)9-5-6-10-26-14(3)23/h7-8,11-12,20H,4-6,9-10H2,1-3H3,(H,21,25)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against Bacillus subtilis DNA polymerase IIIC using [3H]dTMP 250 pM (30 degree C for 10 min)				J Med Chem 48: 7063-74 (2005) Article DOI: 10.1021/jm050517r BindingDB Entry DOI: 10.7270/Q2W66MJN
					More data for this Ligand-Target Pair