null

SMILES: CC1CC(C)CN(C1)c1c(C#N)c(nn1-c1ccc(cn1)S(N)(=O)=O)C(F)(F)F

InChI Key: InChIKey=DZKALGUJNSRMHC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50176553   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50176553 (6-(4-cyano-5-(3,5-dimethylpiperidin-1-yl)-3-(trifl...) Show SMILES CC1CC(C)CN(C1)c1c(C#N)c(nn1-c1ccc(cn1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H19F3N6O2S/c1-10-5-11(2)9-25(8-10)16-13(6-21)15(17(18,19)20)24-26(16)14-4-3-12(7-23-14)29(22,27)28/h3-4,7,10-11H,5,8-9H2,1-2H3,(H2,22,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.87E+3	n/a	n/a	n/a	n/a	n/a	n/a
Veterinary Medicine Research and Development Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against COX2 in canine whole blood				Bioorg Med Chem Lett 16: 288-92 (2005) Article DOI: 10.1016/j.bmcl.2005.10.006 BindingDB Entry DOI: 10.7270/Q2NZ876S
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Canis familiaris)	BDBM50176553 (6-(4-cyano-5-(3,5-dimethylpiperidin-1-yl)-3-(trifl...) Show SMILES CC1CC(C)CN(C1)c1c(C#N)c(nn1-c1ccc(cn1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H19F3N6O2S/c1-10-5-11(2)9-25(8-10)16-13(6-21)15(17(18,19)20)24-26(16)14-4-3-12(7-23-14)29(22,27)28/h3-4,7,10-11H,5,8-9H2,1-2H3,(H2,22,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
Veterinary Medicine Research and Development Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against COX1 in canine whole blood				Bioorg Med Chem Lett 16: 288-92 (2005) Article DOI: 10.1016/j.bmcl.2005.10.006 BindingDB Entry DOI: 10.7270/Q2NZ876S
					More data for this Ligand-Target Pair