BDBM50177008 CHEMBL3814234
SMILES: Cl.CC(C)COc1ccc2cc(ccc2c1)-c1noc(n1)[C@@H]1[C@@H](O)CCN1C(N)=N
InChI Key: InChIKey=PYKJHDPYCHLBFA-APTPAJQOSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sphingosine kinase 1 (SPHK1) (Homo sapiens (Human)) | BDBM50177008 (CHEMBL3814234) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 930 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Tech Curated by ChEMBL | Assay Description Inhibition of human recombinant SphK1 using sphingosine as substrate incubated for 20 mins by scintillation counting analysis in presence of [gamma-3... | ACS Med Chem Lett 7: 229-34 (2016) BindingDB Entry DOI: 10.7270/Q22B90ZN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase types 2 (SphK2) (Homo sapiens (Human)) | BDBM50177008 (CHEMBL3814234) | UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 980 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Tech Curated by ChEMBL | Assay Description Inhibition of human recombinant SphK2 using sphingosine as substrate incubated for 20 mins by scintillation counting analysis in presence of [gamma-3... | ACS Med Chem Lett 7: 229-34 (2016) BindingDB Entry DOI: 10.7270/Q22B90ZN | |||||||||||
More data for this Ligand-Target Pair |