BDBM50177492 CHEMBL204197::methyl (2-{(2S)-2-[(tert-butoxycarbonyl)amino]hexylidene}hydrazino)carbonylcarbamate

SMILES: CCCC[C@H](NC(=O)OC(C)(C)C)C=NNC(=O)NC(=O)OC

InChI Key: InChIKey=YBAKWZAABWFUSD-JTQLQIEISA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50177492   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin K (Homo sapiens (Human))	BDBM50177492 (CHEMBL204197 | methyl (2-{(2S)-2-[(tert-butoxycarb...) Show SMILES CCCC[C@H](NC(=O)OC(C)(C)C)C=NNC(=O)NC(=O)OC |w:14.14| Show InChI InChI=1S/C14H26N4O5/c1-6-7-8-10(16-13(21)23-14(2,3)4)9-15-18-11(19)17-12(20)22-5/h9-10H,6-8H2,1-5H3,(H,16,21)(H2,17,18,19,20)/t10-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of recombinant human cathepsin K in a fluorescence assay				Bioorg Med Chem Lett 16: 978-83 (2006) Article DOI: 10.1016/j.bmcl.2005.10.108 BindingDB Entry DOI: 10.7270/Q2X929VS
					More data for this Ligand-Target Pair