null
SMILES: COc1cccc(COc2ccc(\C=N\NC(=O)c3cc(O)c(O)c(O)c3)cc2)c1
InChI Key: InChIKey=BEXDMMNZSLPJSA-FSJBWODESA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sphingosine kinase 1 (Homo sapiens (Human)) | BDBM50178502![]() (CHEMBL3814880) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.36E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Peking Union Medical College and Chinese Academy of Medical Sciences Curated by ChEMBL | Assay Description Inhibition of GST-tagged full length human recombinant SPHK1 expressed in baculovirus using sphingosine as substrate preincubated for 10 mins measure... | Bioorg Med Chem 24: 3218-30 (2016) BindingDB Entry DOI: 10.7270/Q2377BN8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 2 (Homo sapiens (Human)) | BDBM50178502![]() (CHEMBL3814880) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.17E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Peking Union Medical College and Chinese Academy of Medical Sciences Curated by ChEMBL | Assay Description Inhibition of GST-tagged full length human recombinant SPHK2 expressed in baculovirus using sphingosine as substrate preincubated for 10 mins measure... | Bioorg Med Chem 24: 3218-30 (2016) BindingDB Entry DOI: 10.7270/Q2377BN8 | |||||||||||
More data for this Ligand-Target Pair |