BDBM50178520 CHEMBL202892::N-(benzo[d][1,3]dioxol-5-ylmethyl)-5-(1-methyl-4-(pyridin-4-ylmethylamino)-1H-imidazol-5-yl)-1,3,4-oxadiazol-2-amine

SMILES: Cn1cnc(NCc2ccncc2)c1-c1nnc(NCc2ccc3OCOc3c2)o1

InChI Key: InChIKey=UQKIMTZGDDFLIL-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50178520   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50178520 (CHEMBL202892 | N-(benzo[d][1,3]dioxol-5-ylmethyl)-...) Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(NCc2ccc3OCOc3c2)o1 Show InChI InChI=1S/C20H19N7O3/c1-27-11-24-18(22-9-13-4-6-21-7-5-13)17(27)19-25-26-20(30-19)23-10-14-2-3-15-16(8-14)29-12-28-15/h2-8,11,22H,9-10,12H2,1H3,(H,23,26)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR1 by enzymatic assay				Bioorg Med Chem Lett 16: 1440-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.033 BindingDB Entry DOI: 10.7270/Q2NP240T
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50178520 (CHEMBL202892 | N-(benzo[d][1,3]dioxol-5-ylmethyl)-...) Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(NCc2ccc3OCOc3c2)o1 Show InChI InChI=1S/C20H19N7O3/c1-27-11-24-18(22-9-13-4-6-21-7-5-13)17(27)19-25-26-20(30-19)23-10-14-2-3-15-16(8-14)29-12-28-15/h2-8,11,22H,9-10,12H2,1H3,(H,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2 by enzymatic assay				Bioorg Med Chem Lett 16: 1440-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.033 BindingDB Entry DOI: 10.7270/Q2NP240T
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50178520 (CHEMBL202892 | N-(benzo[d][1,3]dioxol-5-ylmethyl)-...) Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(NCc2ccc3OCOc3c2)o1 Show InChI InChI=1S/C20H19N7O3/c1-27-11-24-18(22-9-13-4-6-21-7-5-13)17(27)19-25-26-20(30-19)23-10-14-2-3-15-16(8-14)29-12-28-15/h2-8,11,22H,9-10,12H2,1H3,(H,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2 in 293 adenovirus transfected kidney cells by cell-based ELISA assay				Bioorg Med Chem Lett 16: 1440-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.033 BindingDB Entry DOI: 10.7270/Q2NP240T
					More data for this Ligand-Target Pair