BDBM50178774 1,2,3,4-tetrahydrocyclopenta[b]indole-3-carboxamide::CHEMBL199068

SMILES: NC(=O)C1CCc2c1[nH]c1ccccc21

InChI Key: InChIKey=UMEZZQGXYXSVLK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50178774   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-Dependent Deacetylase Sirtuin-1 (Homo sapiens (Human))	BDBM50178774 (1,2,3,4-tetrahydrocyclopenta[b]indole-3-carboxamid...) Show SMILES NC(=O)C1CCc2c1[nH]c1ccccc21 Show InChI InChI=1S/C12H12N2O/c13-12(15)9-6-5-8-7-3-1-2-4-10(7)14-11(8)9/h1-4,9,14H,5-6H2,(H2,13,15)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
Elixir Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human SIRT1 expressed in Escherichia coli by fluorimetric assay				J Med Chem 48: 8045-54 (2005) Article DOI: 10.1021/jm050522v BindingDB Entry DOI: 10.7270/Q27D2TPK
					More data for this Ligand-Target Pair