BDBM50178780 6,9-dimethyl-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide::CHEMBL200924

SMILES: Cc1ccc2n(C)c3C(CCCc3c2c1)C(N)=O

InChI Key: InChIKey=KOYPMFDJDZCEPA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50178780   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-Dependent Deacetylase Sirtuin-1 (Homo sapiens (Human))	BDBM50178780 (6,9-dimethyl-2,3,4,9-tetrahydro-1H-carbazole-1-car...) Show SMILES Cc1ccc2n(C)c3C(CCCc3c2c1)C(N)=O Show InChI InChI=1S/C15H18N2O/c1-9-6-7-13-12(8-9)10-4-3-5-11(15(16)18)14(10)17(13)2/h6-8,11H,3-5H2,1-2H3,(H2,16,18)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Elixir Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human SIRT1 expressed in Escherichia coli by fluorimetric assay				J Med Chem 48: 8045-54 (2005) Article DOI: 10.1021/jm050522v BindingDB Entry DOI: 10.7270/Q27D2TPK
					More data for this Ligand-Target Pair