BDBM50178782 2-acetyl-6-chloro-2,3,4,9-tetrahydro-1H-beta-carboline-1-carboxamide::CHEMBL199180

SMILES: CC(=O)N1CCc2c([nH]c3ccc(Cl)cc23)C1C(N)=O

InChI Key: InChIKey=MKYZQLHZXVIJND-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50178782   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-Dependent Deacetylase Sirtuin-1 (Homo sapiens (Human))	BDBM50178782 (2-acetyl-6-chloro-2,3,4,9-tetrahydro-1H-beta-carbo...) Show SMILES CC(=O)N1CCc2c([nH]c3ccc(Cl)cc23)C1C(N)=O Show InChI InChI=1S/C14H14ClN3O2/c1-7(19)18-5-4-9-10-6-8(15)2-3-11(10)17-12(9)13(18)14(16)20/h2-3,6,13,17H,4-5H2,1H3,(H2,16,20)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.99E+4	n/a	n/a	n/a	n/a	n/a	n/a
Elixir Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human SIRT1 expressed in Escherichia coli by fluorimetric assay				J Med Chem 48: 8045-54 (2005) Article DOI: 10.1021/jm050522v BindingDB Entry DOI: 10.7270/Q27D2TPK
					More data for this Ligand-Target Pair