BDBM50178784 6-bromo-2,3,4,9-tetrahydro-1H-carbazole-2-carboxamide::CHEMBL368127

SMILES: NC(=O)C1CCc2c(C1)[nH]c1ccc(Br)cc21

InChI Key: InChIKey=AMMIISIGBOTIGG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50178784   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-Dependent Deacetylase Sirtuin-1 (Homo sapiens (Human))	BDBM50178784 (6-bromo-2,3,4,9-tetrahydro-1H-carbazole-2-carboxam...) Show SMILES NC(=O)C1CCc2c(C1)[nH]c1ccc(Br)cc21 Show InChI InChI=1S/C13H13BrN2O/c14-8-2-4-11-10(6-8)9-3-1-7(13(15)17)5-12(9)16-11/h2,4,6-7,16H,1,3,5H2,(H2,15,17)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.44E+3	n/a	n/a	n/a	n/a	n/a	n/a
Elixir Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human SIRT1 expressed in Escherichia coli by fluorimetric assay				J Med Chem 48: 8045-54 (2005) Article DOI: 10.1021/jm050522v BindingDB Entry DOI: 10.7270/Q27D2TPK
					More data for this Ligand-Target Pair