BDBM50178786 1,6-dimethyl-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide::CHEMBL381204

SMILES: Cc1ccc2[nH]c3c(CCCC3(C)C(N)=O)c2c1

InChI Key: InChIKey=GFJVQPVBWHGBRJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50178786   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-Dependent Deacetylase Sirtuin-1 (Homo sapiens (Human))	BDBM50178786 (1,6-dimethyl-2,3,4,9-tetrahydro-1H-carbazole-1-car...) Show SMILES Cc1ccc2[nH]c3c(CCCC3(C)C(N)=O)c2c1 Show InChI InChI=1S/C15H18N2O/c1-9-5-6-12-11(8-9)10-4-3-7-15(2,14(16)18)13(10)17-12/h5-6,8,17H,3-4,7H2,1-2H3,(H2,16,18)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Elixir Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human SIRT1 expressed in Escherichia coli by fluorimetric assay				J Med Chem 48: 8045-54 (2005) Article DOI: 10.1021/jm050522v BindingDB Entry DOI: 10.7270/Q27D2TPK
					More data for this Ligand-Target Pair