null
SMILES: CCc1ccc(cc1)C(=O)NN(C(=O)c1cc(C)cc(C)c1)C(C)(C)C
InChI Key: InChIKey=QYPNKSZPJQQLRK-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ecdysone receptor/Protein ultraspiracle homolog (Choristoneura fumiferana) | BDBM50178988 (CHEBI:38452 | Tebufenozide) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 0.501 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIRO Materials Science and Engineering and CSIRO Food and Nutritional Sciences Curated by ChEMBL | Assay Description Binding affinity to Choristoneura fumiferana EcR | Pest Manag Sci 67: 1457-67 (2011) Article DOI: 10.1002/ps.2200 BindingDB Entry DOI: 10.7270/Q2B27Z6B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ecdysone receptor/Ultraspiracle (Chilo suppressalis) | BDBM50178988 (CHEBI:38452 | Tebufenozide) | PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIRO Materials Science and Engineering and CSIRO Food and Nutritional Sciences Curated by ChEMBL | Assay Description Binding affinity to Chilo suppressalis (rice stem borer) EcR | Pest Manag Sci 67: 1457-67 (2011) Article DOI: 10.1002/ps.2200 BindingDB Entry DOI: 10.7270/Q2B27Z6B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ecdysone receptor/Gene regulation protein (Heliothis virescens) | BDBM50178988 (CHEBI:38452 | Tebufenozide) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIRO Materials Science and Engineering and CSIRO Food and Nutritional Sciences Curated by ChEMBL | Assay Description Binding affinity to Heliothis virescens (tobacco budworm) EcR | Pest Manag Sci 67: 1457-67 (2011) Article DOI: 10.1002/ps.2200 BindingDB Entry DOI: 10.7270/Q2B27Z6B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ecdysone receptor/USP (Plodia interpunctella) | BDBM50178988 (CHEBI:38452 | Tebufenozide) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIRO Materials Science and Engineering and CSIRO Food and Nutritional Sciences Curated by ChEMBL | Assay Description Binding affinity to Plodia interpunctella (Indian meal moth ) EcR | Pest Manag Sci 67: 1457-67 (2011) Article DOI: 10.1002/ps.2200 BindingDB Entry DOI: 10.7270/Q2B27Z6B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ecdysone receptor/Ultraspiracle (Chironomus tentans) | BDBM50178988 (CHEBI:38452 | Tebufenozide) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIRO Materials Science and Engineering and CSIRO Food and Nutritional Sciences Curated by ChEMBL | Assay Description Binding affinity to Chironomus tentans EcR | Pest Manag Sci 67: 1457-67 (2011) Article DOI: 10.1002/ps.2200 BindingDB Entry DOI: 10.7270/Q2B27Z6B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ultraspiracle isoform-A (Aedes aegypti) | BDBM50178988 (CHEBI:38452 | Tebufenozide) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIRO Materials Science and Engineering and CSIRO Food and Nutritional Sciences Curated by ChEMBL | Assay Description Binding affinity to Aedes aegypti EcR | Pest Manag Sci 67: 1457-67 (2011) Article DOI: 10.1002/ps.2200 BindingDB Entry DOI: 10.7270/Q2B27Z6B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ecdysone receptor/Ultraspiracle protein (Lucilia cuprina) | BDBM50178988 (CHEBI:38452 | Tebufenozide) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 158 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIRO Materials Science and Engineering and CSIRO Food and Nutritional Sciences Curated by ChEMBL | Assay Description Binding affinity to Lucilia cuprina EcR | Pest Manag Sci 67: 1457-67 (2011) Article DOI: 10.1002/ps.2200 BindingDB Entry DOI: 10.7270/Q2B27Z6B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein ultraspiracle (Drosophila melanogaster) | BDBM50178988 (CHEBI:38452 | Tebufenozide) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 251 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIRO Materials Science and Engineering and CSIRO Food and Nutritional Sciences Curated by ChEMBL | Assay Description Binding affinity to Drosophila melanogaster EcR | Pest Manag Sci 67: 1457-67 (2011) Article DOI: 10.1002/ps.2200 BindingDB Entry DOI: 10.7270/Q2B27Z6B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ultraspiracle isoform B (Leptinotarsa decemlineata) | BDBM50178988 (CHEBI:38452 | Tebufenozide) | PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIRO Materials Science and Engineering and CSIRO Food and Nutritional Sciences Curated by ChEMBL | Assay Description Binding affinity to Leptinotarsa decemlineata EcR | Pest Manag Sci 67: 1457-67 (2011) Article DOI: 10.1002/ps.2200 BindingDB Entry DOI: 10.7270/Q2B27Z6B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ecdysone receptor/Ultraspiracle (Anthonomus grandis-Leptinotarsa decemlineata) | BDBM50178988 (CHEBI:38452 | Tebufenozide) | PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.26E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIRO Materials Science and Engineering and CSIRO Food and Nutritional Sciences Curated by ChEMBL | Assay Description Binding affinity to Anthonomus grandis ecdysone receptor (EcR) | Pest Manag Sci 67: 1457-67 (2011) Article DOI: 10.1002/ps.2200 BindingDB Entry DOI: 10.7270/Q2B27Z6B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ultraspiracle (Nezara viridula) | BDBM50178988 (CHEBI:38452 | Tebufenozide) | PDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.68E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIRO Materials Science and Engineering and CSIRO Food and Nutritional Sciences Curated by ChEMBL | Assay Description Displacement of [3H]PonA from recombinant Nezara viridula EcR10 | Pest Manag Sci 67: 1457-67 (2011) Article DOI: 10.1002/ps.2200 BindingDB Entry DOI: 10.7270/Q2B27Z6B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ultraspiracle (Nezara viridula) | BDBM50178988 (CHEBI:38452 | Tebufenozide) | PDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIRO Materials Science and Engineering and CSIRO Food and Nutritional Sciences Curated by ChEMBL | Assay Description Binding affinity to Nezara viridula EcR10 | Pest Manag Sci 67: 1457-67 (2011) Article DOI: 10.1002/ps.2200 BindingDB Entry DOI: 10.7270/Q2B27Z6B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ultraspiracle (Nezara viridula) | BDBM50178988 (CHEBI:38452 | Tebufenozide) | PDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 2.39E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIRO Materials Science and Engineering and CSIRO Food and Nutritional Sciences Curated by ChEMBL | Assay Description Displacement of [3H]PonA from recombinant Nezara viridula EcR11 | Pest Manag Sci 67: 1457-67 (2011) Article DOI: 10.1002/ps.2200 BindingDB Entry DOI: 10.7270/Q2B27Z6B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ultraspiracle (Nezara viridula) | BDBM50178988 (CHEBI:38452 | Tebufenozide) | PDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 2.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIRO Materials Science and Engineering and CSIRO Food and Nutritional Sciences Curated by ChEMBL | Assay Description Binding affinity to Nezara viridula EcR | Pest Manag Sci 67: 1457-67 (2011) Article DOI: 10.1002/ps.2200 BindingDB Entry DOI: 10.7270/Q2B27Z6B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ultraspiracle (Nezara viridula) | BDBM50178988 (CHEBI:38452 | Tebufenozide) | PDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 2.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIRO Materials Science and Engineering and CSIRO Food and Nutritional Sciences Curated by ChEMBL | Assay Description Binding affinity to Nezara viridula EcR11 | Pest Manag Sci 67: 1457-67 (2011) Article DOI: 10.1002/ps.2200 BindingDB Entry DOI: 10.7270/Q2B27Z6B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ecdysone receptor/Nuclear receptor RXR-l (Locusta migratoria) | BDBM50178988 (CHEBI:38452 | Tebufenozide) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIRO Materials Science and Engineering and CSIRO Food and Nutritional Sciences Curated by ChEMBL | Assay Description Binding affinity to Locusta migratoria ecdysone receptor (EcR) | Pest Manag Sci 67: 1457-67 (2011) Article DOI: 10.1002/ps.2200 BindingDB Entry DOI: 10.7270/Q2B27Z6B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ecdysone receptor/Ultraspiracle protein (Myzus persicae) | BDBM50178988 (CHEBI:38452 | Tebufenozide) | Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | <1.26E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIRO Materials Science and Engineering and CSIRO Food and Nutritional Sciences Curated by ChEMBL | Assay Description Binding affinity to Myzus persicae EcR (green peach aphid) | Pest Manag Sci 67: 1457-67 (2011) Article DOI: 10.1002/ps.2200 BindingDB Entry DOI: 10.7270/Q2B27Z6B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ecdysone receptor/Ultraspiracle protein (Bemisia tabaci) | BDBM50178988 (CHEBI:38452 | Tebufenozide) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | <5.01E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIRO Materials Science and Engineering and CSIRO Food and Nutritional Sciences Curated by ChEMBL | Assay Description Binding affinity to Bemisia tabaci (sweet potato whitefly) ecdysone receptor (EcR) | Pest Manag Sci 67: 1457-67 (2011) Article DOI: 10.1002/ps.2200 BindingDB Entry DOI: 10.7270/Q2B27Z6B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ecdysone receptor (Bombyx mori) | BDBM50178988 (CHEBI:38452 | Tebufenozide) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a |
Ghent University Curated by ChEMBL | Assay Description Agonist activity at ecdysone receptor in Bombyx mori Bm5 cells after 24 hr by luciferase reporter gene assay | Pest Manag Sci 66: 1215-29 (2010) Article DOI: 10.1002/ps.1998 BindingDB Entry DOI: 10.7270/Q2FT8PXB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein ultraspiracle (Drosophila melanogaster) | BDBM50178988 (CHEBI:38452 | Tebufenozide) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 525 | n/a | n/a | n/a | n/a |
Ghent University Curated by ChEMBL | Assay Description Agonist activity at ecdysone receptor in Drosophila melanogaster B2 cells assessed as reduction in cell density | Pest Manag Sci 66: 1215-29 (2010) Article DOI: 10.1002/ps.1998 BindingDB Entry DOI: 10.7270/Q2FT8PXB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ecdysone receptor (Spodoptera littoralis) | BDBM50178988 (CHEBI:38452 | Tebufenozide) | PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a |
Ghent University Curated by ChEMBL | Assay Description Agonist activity at ecdysone receptor in Spodoptera littoralis Sl2 cells after 24 hr by luciferase reporter gene assay | Pest Manag Sci 66: 526-35 (2010) Article DOI: 10.1002/ps.1903 BindingDB Entry DOI: 10.7270/Q2KK9FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ecdysone receptor (Bombyx mori) | BDBM50178988 (CHEBI:38452 | Tebufenozide) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a |
Ghent University Curated by ChEMBL | Assay Description Agonist activity at ecdysone receptor in Bombyx mori Bm5 cells after 24 hr by luciferase reporter gene assay | Pest Manag Sci 66: 526-35 (2010) Article DOI: 10.1002/ps.1903 BindingDB Entry DOI: 10.7270/Q2KK9FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ultraspiracle (Nezara viridula) | BDBM50178988 (CHEBI:38452 | Tebufenozide) | PDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIRO Materials Science and Engineering and CSIRO Food and Nutritional Sciences Curated by ChEMBL | Assay Description Displacement of [3H]PonA from recombinant Nezara viridula EcR11 | Pest Manag Sci 67: 1457-67 (2011) Article DOI: 10.1002/ps.2200 BindingDB Entry DOI: 10.7270/Q2B27Z6B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein ultraspiracle (Drosophila melanogaster) | BDBM50178988 (CHEBI:38452 | Tebufenozide) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 6.61E+3 | n/a | n/a | n/a | n/a |
Ghent University Curated by ChEMBL | Assay Description Agonist activity at ecdysone receptor in Drosophila melanogaster S2 cells after 24 hr by luciferase reporter gene assay | Pest Manag Sci 66: 1215-29 (2010) Article DOI: 10.1002/ps.1998 BindingDB Entry DOI: 10.7270/Q2FT8PXB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50178988 (CHEBI:38452 | Tebufenozide) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.15E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University Curated by ChEMBL | Assay Description Inhibition of human P-glycoprotein transfected in pig LLC-GA5-COL150 cells assessed as quinidine transport from apical to basolateral side preincubat... | Bioorg Med Chem 24: 3184-91 (2016) BindingDB Entry DOI: 10.7270/Q2611275 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ultraspiracle (Nezara viridula) | BDBM50178988 (CHEBI:38452 | Tebufenozide) | PDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIRO Materials Science and Engineering and CSIRO Food and Nutritional Sciences Curated by ChEMBL | Assay Description Displacement of [3H]PonA from recombinant Nezara viridula EcR10 | Pest Manag Sci 67: 1457-67 (2011) Article DOI: 10.1002/ps.2200 BindingDB Entry DOI: 10.7270/Q2B27Z6B | |||||||||||
More data for this Ligand-Target Pair |