null

SMILES: CC1(C)COC(=O)N1CC1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1)C1CCCCC1

InChI Key: InChIKey=YHYBBOPOIUAVHY-FIRIVFDPSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50179134   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 3 (Homo sapiens (Human))	BDBM50179134 ((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...) Show SMILES CC1(C)COC(=O)N1CC1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1)C1CCCCC1 Show InChI InChI=1S/C36H47ClN4O4/c1-35(2)24-45-34(44)41(35)23-36(28-10-4-3-5-11-28)16-18-40(19-17-36)33(43)31(20-25-12-14-29(37)15-13-25)39-32(42)30-21-26-8-6-7-9-27(26)22-38-30/h6-9,12-15,28,30-31,38H,3-5,10-11,16-24H2,1-2H3,(H,39,42)/t30-,31-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]NDP-alpha-MSH from human MC3R expressed in CHO cells				Bioorg Med Chem Lett 16: 1130-3 (2006) Article DOI: 10.1016/j.bmcl.2005.11.095 BindingDB Entry DOI: 10.7270/Q2NG4Q5S
					More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Homo sapiens (Human))	BDBM50179134 ((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...) Show SMILES CC1(C)COC(=O)N1CC1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1)C1CCCCC1 Show InChI InChI=1S/C36H47ClN4O4/c1-35(2)24-45-34(44)41(35)23-36(28-10-4-3-5-11-28)16-18-40(19-17-36)33(43)31(20-25-12-14-29(37)15-13-25)39-32(42)30-21-26-8-6-7-9-27(26)22-38-30/h6-9,12-15,28,30-31,38H,3-5,10-11,16-24H2,1-2H3,(H,39,42)/t30-,31-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	550	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Activity against human MC1BR by cAMP accumulation				Bioorg Med Chem Lett 16: 1130-3 (2006) Article DOI: 10.1016/j.bmcl.2005.11.095 BindingDB Entry DOI: 10.7270/Q2NG4Q5S
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50179134 ((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...) Show SMILES CC1(C)COC(=O)N1CC1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1)C1CCCCC1 Show InChI InChI=1S/C36H47ClN4O4/c1-35(2)24-45-34(44)41(35)23-36(28-10-4-3-5-11-28)16-18-40(19-17-36)33(43)31(20-25-12-14-29(37)15-13-25)39-32(42)30-21-26-8-6-7-9-27(26)22-38-30/h6-9,12-15,28,30-31,38H,3-5,10-11,16-24H2,1-2H3,(H,39,42)/t30-,31-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.40	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Activity against human MC4R by cAMP accumulation				Bioorg Med Chem Lett 16: 1130-3 (2006) Article DOI: 10.1016/j.bmcl.2005.11.095 BindingDB Entry DOI: 10.7270/Q2NG4Q5S
					More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Homo sapiens (Human))	BDBM50179134 ((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...) Show SMILES CC1(C)COC(=O)N1CC1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1)C1CCCCC1 Show InChI InChI=1S/C36H47ClN4O4/c1-35(2)24-45-34(44)41(35)23-36(28-10-4-3-5-11-28)16-18-40(19-17-36)33(43)31(20-25-12-14-29(37)15-13-25)39-32(42)30-21-26-8-6-7-9-27(26)22-38-30/h6-9,12-15,28,30-31,38H,3-5,10-11,16-24H2,1-2H3,(H,39,42)/t30-,31-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Activity against human MC1BR by cAMP accumulation				Bioorg Med Chem Lett 16: 1130-3 (2006) Article DOI: 10.1016/j.bmcl.2005.11.095 BindingDB Entry DOI: 10.7270/Q2NG4Q5S
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (Homo sapiens (Human))	BDBM50179134 ((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...) Show SMILES CC1(C)COC(=O)N1CC1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1)C1CCCCC1 Show InChI InChI=1S/C36H47ClN4O4/c1-35(2)24-45-34(44)41(35)23-36(28-10-4-3-5-11-28)16-18-40(19-17-36)33(43)31(20-25-12-14-29(37)15-13-25)39-32(42)30-21-26-8-6-7-9-27(26)22-38-30/h6-9,12-15,28,30-31,38H,3-5,10-11,16-24H2,1-2H3,(H,39,42)/t30-,31-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	340	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Activity against human MC5R by cAMP accumulation				Bioorg Med Chem Lett 16: 1130-3 (2006) Article DOI: 10.1016/j.bmcl.2005.11.095 BindingDB Entry DOI: 10.7270/Q2NG4Q5S
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50179134 ((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...) Show SMILES CC1(C)COC(=O)N1CC1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1)C1CCCCC1 Show InChI InChI=1S/C36H47ClN4O4/c1-35(2)24-45-34(44)41(35)23-36(28-10-4-3-5-11-28)16-18-40(19-17-36)33(43)31(20-25-12-14-29(37)15-13-25)39-32(42)30-21-26-8-6-7-9-27(26)22-38-30/h6-9,12-15,28,30-31,38H,3-5,10-11,16-24H2,1-2H3,(H,39,42)/t30-,31-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Activity against human MC4R by cAMP accumulation				Bioorg Med Chem Lett 16: 1130-3 (2006) Article DOI: 10.1016/j.bmcl.2005.11.095 BindingDB Entry DOI: 10.7270/Q2NG4Q5S
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (Homo sapiens (Human))	BDBM50179134 ((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...) Show SMILES CC1(C)COC(=O)N1CC1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1)C1CCCCC1 Show InChI InChI=1S/C36H47ClN4O4/c1-35(2)24-45-34(44)41(35)23-36(28-10-4-3-5-11-28)16-18-40(19-17-36)33(43)31(20-25-12-14-29(37)15-13-25)39-32(42)30-21-26-8-6-7-9-27(26)22-38-30/h6-9,12-15,28,30-31,38H,3-5,10-11,16-24H2,1-2H3,(H,39,42)/t30-,31-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in CHO cells				Bioorg Med Chem Lett 16: 1130-3 (2006) Article DOI: 10.1016/j.bmcl.2005.11.095 BindingDB Entry DOI: 10.7270/Q2NG4Q5S
					More data for this Ligand-Target Pair