BDBM50179488 CHEMBL3814807

SMILES: CCCc1cc(ccc1Oc1ccc(CCN2C(=O)NC(C)(C2=O)c2ccc(OC(C)C)cc2)cc1)C(O)(C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=AGGRXWJTRGYHGV-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50179488   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50179488 (CHEMBL3814807) Show SMILES CCCc1cc(ccc1Oc1ccc(CCN2C(=O)NC(C)(C2=O)c2ccc(OC(C)C)cc2)cc1)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C33H34F6N2O5/c1-5-6-22-19-24(31(44,32(34,35)36)33(37,38)39)11-16-27(22)46-26-12-7-21(8-13-26)17-18-41-28(42)30(4,40-29(41)43)23-9-14-25(15-10-23)45-20(2)3/h7-16,19-20,44H,5-6,17-18H2,1-4H3,(H,40,43)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.88E+3	n/a	n/a	n/a	n/a
Kowa Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at GAL4 fused LXRbeta-LBD (unknown origin) transfected in CHOK1 cells after 24 hrs by luciferase reporter gene assay				Bioorg Med Chem 24: 3436-46 (2016) BindingDB Entry DOI: 10.7270/Q2DJ5HJ4
					More data for this Ligand-Target Pair