BDBM50179491 CHEMBL3814806

SMILES: CCCc1cc(ccc1Oc1ccc(cc1)C(O)CN1C(=O)NC(C)(C1=O)c1ccc(OC(C)C)cc1)C(O)(C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=NUKARMLSXBVHLP-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50179491   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50179491 (CHEMBL3814806) Show SMILES CCCc1cc(ccc1Oc1ccc(cc1)C(O)CN1C(=O)NC(C)(C1=O)c1ccc(OC(C)C)cc1)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C33H34F6N2O6/c1-5-6-21-17-23(31(45,32(34,35)36)33(37,38)39)11-16-27(21)47-25-12-7-20(8-13-25)26(42)18-41-28(43)30(4,40-29(41)44)22-9-14-24(15-10-22)46-19(2)3/h7-17,19,26,42,45H,5-6,18H2,1-4H3,(H,40,44)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	2.33E+3	n/a	n/a	n/a	n/a
Kowa Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at GAL4 fused LXRbeta-LBD (unknown origin) transfected in CHOK1 cells after 24 hrs by luciferase reporter gene assay				Bioorg Med Chem 24: 3436-46 (2016) BindingDB Entry DOI: 10.7270/Q2DJ5HJ4
					More data for this Ligand-Target Pair