BDBM50179684 (2S,3R,4S,5S,6R)-2-(3-(3-fluoro-4-methylbenzyl)-1H-indol-4-yloxy)-6-(hydroxymethyl)-tetrahydro-2H-pyran-3,4,5-triol::CHEMBL205459

SMILES: Cc1ccc(Cc2c[nH]c3cccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c23)cc1F

InChI Key: InChIKey=QVTUZKIVMRMMGD-MIUGBVLSSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50179684   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50179684 ((2S,3R,4S,5S,6R)-2-(3-(3-fluoro-4-methylbenzyl)-1H...) Show SMILES Cc1ccc(Cc2c[nH]c3cccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c23)cc1F Show InChI InChI=1S/C22H24FNO6/c1-11-5-6-12(8-14(11)23)7-13-9-24-15-3-2-4-16(18(13)15)29-22-21(28)20(27)19(26)17(10-25)30-22/h2-6,8-9,17,19-22,24-28H,7,10H2,1H3/t17-,19-,20+,21-,22-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	99	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory activity aginst SGLT2 expressed in CHO-K1 cells				Bioorg Med Chem Lett 16: 1696-701 (2006) Article DOI: 10.1016/j.bmcl.2005.12.006 BindingDB Entry DOI: 10.7270/Q22J6BDJ
					More data for this Ligand-Target Pair