BDBM50179685 (2S,3R,4R,5S,6R)-2-(3-(4-ethylbenzyl)-1H-indol-5-yl)-6-(hydroxymethyl)-tetrahydro-2H-pyran-3,4,5-triol::CHEMBL377301

SMILES: CCc1ccc(Cc2c[nH]c3ccc(cc23)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1

InChI Key: InChIKey=JUKBYZVOZNYJIY-ZQGJOIPISA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50179685   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50179685 ((2S,3R,4R,5S,6R)-2-(3-(4-ethylbenzyl)-1H-indol-5-y...) Show SMILES CCc1ccc(Cc2c[nH]c3ccc(cc23)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 Show InChI InChI=1S/C23H27NO5/c1-2-13-3-5-14(6-4-13)9-16-11-24-18-8-7-15(10-17(16)18)23-22(28)21(27)20(26)19(12-25)29-23/h3-8,10-11,19-28H,2,9,12H2,1H3/t19-,20-,21+,22-,23+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	132	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory activity aginst SGLT2 expressed in CHO-K1 cells				Bioorg Med Chem Lett 16: 1696-701 (2006) Article DOI: 10.1016/j.bmcl.2005.12.006 BindingDB Entry DOI: 10.7270/Q22J6BDJ
					More data for this Ligand-Target Pair