BDBM50179750 (S)-2-((S)-2-(benzyloxycarbonyl)-4-methylpentanamido)-4-methylpentanoic acid::CHEMBL203568
SMILES: CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C(O)=O
InChI Key: InChIKey=XGJGWYRHLPSMLW-IRXDYDNUSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Calpain 1/small subunit 1 (Homo sapiens (Human)) | BDBM50179750 ((S)-2-((S)-2-(benzyloxycarbonyl)-4-methylpentanami...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Inhibition of isolated human calpain1 | Bioorg Med Chem Lett 16: 1586-9 (2006) Article DOI: 10.1016/j.bmcl.2005.12.036 BindingDB Entry DOI: 10.7270/Q2T15367 | |||||||||||
More data for this Ligand-Target Pair |