BDBM50180085 4-[2-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-indol-3-yl]-ethoxy]2-fluorobenzoic acid::CHEMBL199533

SMILES: Cc1c(CCOc2ccc(C(O)=O)c(F)c2)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1

InChI Key: InChIKey=SFKYNISBCJFHBK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50180085   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cPLA2 C2 (Homo sapiens (Human))	BDBM50180085 (4-[2-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-indo...) Show SMILES Cc1c(CCOc2ccc(C(O)=O)c(F)c2)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H25ClFNO3/c1-20-25(16-17-37-24-13-14-26(31(35)36)28(33)19-24)27-18-23(32)12-15-29(27)34(20)30(21-8-4-2-5-9-21)22-10-6-3-7-11-22/h2-15,18-19,30H,16-17H2,1H3,(H,35,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay				J Med Chem 49: 135-58 (2006) Article DOI: 10.1021/jm0507882 BindingDB Entry DOI: 10.7270/Q2MC8ZMP
					More data for this Ligand-Target Pair