BDBM50180374 3-(2-methoxypyridin-4-yl)-7-(trifluoromethyl)imidazo[1,2-a]pyrimidine::CHEMBL383467

SMILES: COc1cc(ccn1)-c1cnc2nc(ccn12)C(F)(F)F

InChI Key: InChIKey=HAHDKXDDOBLEEH-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50180374   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA receptor alpha-1/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50180374 (3-(2-methoxypyridin-4-yl)-7-(trifluoromethyl)imida...) Show SMILES COc1cc(ccn1)-c1cnc2nc(ccn12)C(F)(F)F Show InChI InChI=1S/C13H9F3N4O/c1-21-11-6-8(2-4-17-11)9-7-18-12-19-10(13(14,15)16)3-5-20(9)12/h2-7H,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha1 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1175-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.112 BindingDB Entry DOI: 10.7270/Q2FN15SZ
					More data for this Ligand-Target Pair
GABA receptor alpha-3/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50180374 (3-(2-methoxypyridin-4-yl)-7-(trifluoromethyl)imida...) Show SMILES COc1cc(ccn1)-c1cnc2nc(ccn12)C(F)(F)F Show InChI InChI=1S/C13H9F3N4O/c1-21-11-6-8(2-4-17-11)9-7-18-12-19-10(13(14,15)16)3-5-20(9)12/h2-7H,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha3 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1175-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.112 BindingDB Entry DOI: 10.7270/Q2FN15SZ
					More data for this Ligand-Target Pair