BDBM50181674 6'-methoxy-6-oxo-1,6-dihydro-[3,3']bipyridinyl-5-carboxylic acid [4-(4-methyl-piperazin-1-ylmethyl)-phenyl]-amide::CHEMBL203354

SMILES: COc1ccc(cn1)-c1c[nH]c(=O)c(c1)C(=O)Nc1ccc(CN2CCN(C)CC2)cc1

InChI Key: InChIKey=LSBZCOGIERJUBR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50181674   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin receptor (Homo sapiens (Human))	BDBM50181674 (6'-methoxy-6-oxo-1,6-dihydro-[3,3']bipyridinyl-5-c...) Show SMILES COc1ccc(cn1)-c1c[nH]c(=O)c(c1)C(=O)Nc1ccc(CN2CCN(C)CC2)cc1 Show InChI InChI=1S/C24H27N5O3/c1-28-9-11-29(12-10-28)16-17-3-6-20(7-4-17)27-24(31)21-13-19(15-26-23(21)30)18-5-8-22(32-2)25-14-18/h3-8,13-15H,9-12,16H2,1-2H3,(H,26,30)(H,27,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.38E+4	n/a	n/a	n/a	n/a	n/a	n/a
ChemBridge Research Laboratories and ChemBridge Corporation Curated by ChEMBL					Assay Description Inhibitory activity against IRK				J Med Chem 49: 1006-15 (2006) Article DOI: 10.1021/jm050824x BindingDB Entry DOI: 10.7270/Q2H994T6
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50181674 (6'-methoxy-6-oxo-1,6-dihydro-[3,3']bipyridinyl-5-c...) Show SMILES COc1ccc(cn1)-c1c[nH]c(=O)c(c1)C(=O)Nc1ccc(CN2CCN(C)CC2)cc1 Show InChI InChI=1S/C24H27N5O3/c1-28-9-11-29(12-10-28)16-17-3-6-20(7-4-17)27-24(31)21-13-19(15-26-23(21)30)18-5-8-22(32-2)25-14-18/h3-8,13-15H,9-12,16H2,1-2H3,(H,26,30)(H,27,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ChemBridge Research Laboratories and ChemBridge Corporation Curated by ChEMBL					Assay Description Inhibitory activity against ALK				J Med Chem 49: 1006-15 (2006) Article DOI: 10.1021/jm050824x BindingDB Entry DOI: 10.7270/Q2H994T6
					More data for this Ligand-Target Pair