BDBM50181735 5-(5-[2-chloro-5-(trifluoromethyl)phenyl]-furan-2-methylene)-3-(benzenesulfonylamino)-4-oxo-2-thionothiazolidine::CHEMBL381101

SMILES: FC(F)(F)c1ccc(Cl)c(c1)-c1ccc(C=C2SC(=S)N(NS(=O)(=O)c3ccccc3)C2=O)o1

InChI Key: InChIKey=WAUSETCVJRWNBY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181735   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50181735 (5-(5-[2-chloro-5-(trifluoromethyl)phenyl]-furan-2-...) Show SMILES FC(F)(F)c1ccc(Cl)c(c1)-c1ccc(C=C2SC(=S)N(NS(=O)(=O)c3ccccc3)C2=O)o1 |w:15.15| Show InChI InChI=1S/C21H12ClF3N2O4S3/c22-16-8-6-12(21(23,24)25)10-15(16)17-9-7-13(31-17)11-18-19(28)27(20(32)33-18)26-34(29,30)14-4-2-1-3-5-14/h1-11,26H	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5b RNA polymerase				J Med Chem 49: 1034-46 (2006) Article DOI: 10.1021/jm050859x BindingDB Entry DOI: 10.7270/Q2CJ8D3W
					More data for this Ligand-Target Pair