BDBM50182348 5-(methylsulfonyl)-2-(5-(4-(5-methylthiazol-4-yl)phenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)pyridine::CHEMBL206402

SMILES: Cc1scnc1-c1ccc(cc1)-c1cc(nn1-c1ccc(cn1)S(C)(=O)=O)C(F)(F)F

InChI Key: InChIKey=RJDSGKQETJPZIH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50182348   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50182348 (5-(methylsulfonyl)-2-(5-(4-(5-methylthiazol-4-yl)p...) Show SMILES Cc1scnc1-c1ccc(cc1)-c1cc(nn1-c1ccc(cn1)S(C)(=O)=O)C(F)(F)F Show InChI InChI=1S/C20H15F3N4O2S2/c1-12-19(25-11-30-12)14-5-3-13(4-6-14)16-9-17(20(21,22)23)26-27(16)18-8-7-15(10-24-18)31(2,28)29/h3-11H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
Veterinary Medicine Research and Development Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of COX2 in canine whole blood				Bioorg Med Chem Lett 16: 2076-80 (2006) Article DOI: 10.1016/j.bmcl.2006.01.059 BindingDB Entry DOI: 10.7270/Q28K78PW
					More data for this Ligand-Target Pair