BDBM50182350 2-(furan-2-yl)-5-(1-(5-(methylsulfonyl)pyridin-2-yl)-3-(trifluoromethyl)-1H-pyrazol-5-yl)benzamide::CHEMBL205308

SMILES: CS(=O)(=O)c1ccc(nc1)-n1nc(cc1-c1ccc(-c2ccco2)c(c1)C(N)=O)C(F)(F)F

InChI Key: InChIKey=RTYBDSFNSYNBEF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50182350   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Canis familiaris)	BDBM50182350 (2-(furan-2-yl)-5-(1-(5-(methylsulfonyl)pyridin-2-y...) Show SMILES CS(=O)(=O)c1ccc(nc1)-n1nc(cc1-c1ccc(-c2ccco2)c(c1)C(N)=O)C(F)(F)F Show InChI InChI=1S/C21H15F3N4O4S/c1-33(30,31)13-5-7-19(26-11-13)28-16(10-18(27-28)21(22,23)24)12-4-6-14(15(9-12)20(25)29)17-3-2-8-32-17/h2-11H,1H3,(H2,25,29)	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Veterinary Medicine Research and Development Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of COX2 in canine whole blood				Bioorg Med Chem Lett 16: 2076-80 (2006) Article DOI: 10.1016/j.bmcl.2006.01.059 BindingDB Entry DOI: 10.7270/Q28K78PW
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Canis familiaris)	BDBM50182350 (2-(furan-2-yl)-5-(1-(5-(methylsulfonyl)pyridin-2-y...) Show SMILES CS(=O)(=O)c1ccc(nc1)-n1nc(cc1-c1ccc(-c2ccco2)c(c1)C(N)=O)C(F)(F)F Show InChI InChI=1S/C21H15F3N4O4S/c1-33(30,31)13-5-7-19(26-11-13)28-16(10-18(27-28)21(22,23)24)12-4-6-14(15(9-12)20(25)29)17-3-2-8-32-17/h2-11H,1H3,(H2,25,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Veterinary Medicine Research and Development Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of COX1 in canine whole blood				Bioorg Med Chem Lett 16: 2076-80 (2006) Article DOI: 10.1016/j.bmcl.2006.01.059 BindingDB Entry DOI: 10.7270/Q28K78PW
					More data for this Ligand-Target Pair