BDBM50182351 2-(5-(3-chloro-4-(thiazol-4-yl)phenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)-5-(methylsulfonyl)pyridine::CHEMBL377797
SMILES: CS(=O)(=O)c1ccc(nc1)-n1nc(cc1-c1ccc(-c2cscn2)c(Cl)c1)C(F)(F)F
InChI Key: InChIKey=HKZPIIJDRGENAW-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin G/H synthase 2 (Canis familiaris) | BDBM50182351 (2-(5-(3-chloro-4-(thiazol-4-yl)phenyl)-3-(trifluor...) | PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
Veterinary Medicine Research and Development Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of COX2 in canine whole blood | Bioorg Med Chem Lett 16: 2076-80 (2006) Article DOI: 10.1016/j.bmcl.2006.01.059 BindingDB Entry DOI: 10.7270/Q28K78PW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Canis familiaris) | BDBM50182351 (2-(5-(3-chloro-4-(thiazol-4-yl)phenyl)-3-(trifluor...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Veterinary Medicine Research and Development Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of COX1 in canine whole blood | Bioorg Med Chem Lett 16: 2076-80 (2006) Article DOI: 10.1016/j.bmcl.2006.01.059 BindingDB Entry DOI: 10.7270/Q28K78PW | |||||||||||
More data for this Ligand-Target Pair |