BDBM50182621 1-(6-hydroxy-7-methoxy-4-(naphthalen-1-ylmethoxy)benzofuran-5-yl)ethanone::CHEMBL202692

SMILES: COc1c(O)c(C(C)=O)c(OCc2cccc3ccccc23)c2ccoc12

InChI Key: InChIKey=RMJVHDRIYREEHY-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50182621   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated potassium channel subunit Kv1.3 (Mus musculus)	BDBM50182621 (1-(6-hydroxy-7-methoxy-4-(naphthalen-1-ylmethoxy)b...) Show SMILES COc1c(O)c(C(C)=O)c(OCc2cccc3ccccc23)c2ccoc12 Show InChI InChI=1S/C22H18O5/c1-13(23)18-19(24)22(25-2)21-17(10-11-26-21)20(18)27-12-15-8-5-7-14-6-3-4-9-16(14)15/h3-11,24H,12H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a
Institute of Medical Research Biotechnology Centre Curated by ChEMBL					Assay Description Effect on blockade of mouse Kv1.3 channel expressed in L929 cells				J Med Chem 49: 1433-41 (2006) Article DOI: 10.1021/jm050839v BindingDB Entry DOI: 10.7270/Q2KW5FM6
					More data for this Ligand-Target Pair