BDBM50183278 CHEMBL3819262

SMILES: Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)O[C@@H]2[C@H](O)[C@@H](COP(O)(=O)O[C@@H]3[C@H](O)[C@@H](COP(O)(=O)O[C@@H]4[C@H](O)[C@@H](COP(O)(O)=O)O[C@H]4n4ccc(=O)[nH]c4=O)O[C@H]3n3cnc4c(N)ncnc34)O[C@H]2n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O

InChI Key: InChIKey=UFIRYHFLJQOEAU-PFILIUQBSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50183278   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNase L (Homo sapiens (Human))	BDBM50183278 (CHEMBL3819262) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)O[C@@H]2[C@H](O)[C@@H](COP(O)(=O)O[C@@H]3[C@H](O)[C@@H](COP(O)(=O)O[C@@H]4[C@H](O)[C@@H](COP(O)(O)=O)O[C@H]4n4ccc(=O)[nH]c4=O)O[C@H]3n3cnc4c(N)ncnc34)O[C@H]2n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C39H49N17O27P4/c40-29-18-32(46-7-43-29)54(10-49-18)35-25(62)21(58)13(77-35)4-74-85(67,68)82-27-23(60)16(80-37(27)55-11-50-19-30(41)44-8-47-33(19)55)6-76-87(71,72)83-28-24(61)15(79-38(28)56-12-51-20-31(42)45-9-48-34(20)56)5-75-86(69,70)81-26-22(59)14(3-73-84(64,65)66)78-36(26)53-2-1-17(57)52-39(53)63/h1-2,7-16,21-28,35-38,58-62H,3-6H2,(H,67,68)(H,69,70)(H,71,72)(H2,40,43,46)(H2,41,44,47)(H2,42,45,48)(H,52,57,63)(H2,64,65,66)/t13-,14-,15-,16-,21-,22-,23-,24-,25-,26-,27-,28-,35-,36-,37-,38-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	84	n/a	n/a	n/a	n/a
Gifu University Curated by ChEMBL					Assay Description Induction of recombinant human RNase L activity expressed in Escherichia coli using F-5'-r(C11U2C7)-3' as substrate by polyacrylamide gel electrophor...				Bioorg Med Chem 24: 3870-4 (2016) BindingDB Entry DOI: 10.7270/Q2RF5WZ4
					More data for this Ligand-Target Pair