Found 6 hits for monomerid = 50183730 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50183730
(CHEMBL380895 | N-(4-(2-(hydroxyamino)-2-oxoethyl)-...)Show SMILES CN1CCC(CC(=O)NO)(CC1)NC(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 Show InChI InChI=1S/C26H30N4O4/c1-18-15-20(22-5-3-4-6-23(22)27-18)17-34-21-9-7-19(8-10-21)25(32)28-26(16-24(31)29-33)11-13-30(2)14-12-26/h3-10,15,33H,11-14,16-17H2,1-2H3,(H,28,32)(H,29,31) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >2.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding affinity to MMP9 |
Bioorg Med Chem Lett 16: 2699-704 (2006)
Article DOI: 10.1016/j.bmcl.2006.02.015 BindingDB Entry DOI: 10.7270/Q2TB16H3 |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50183730
(CHEMBL380895 | N-(4-(2-(hydroxyamino)-2-oxoethyl)-...)Show SMILES CN1CCC(CC(=O)NO)(CC1)NC(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 Show InChI InChI=1S/C26H30N4O4/c1-18-15-20(22-5-3-4-6-23(22)27-18)17-34-21-9-7-19(8-10-21)25(32)28-26(16-24(31)29-33)11-13-30(2)14-12-26/h3-10,15,33H,11-14,16-17H2,1-2H3,(H,28,32)(H,29,31) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >3.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding affinity to MMP2 |
Bioorg Med Chem Lett 16: 2699-704 (2006)
Article DOI: 10.1016/j.bmcl.2006.02.015 BindingDB Entry DOI: 10.7270/Q2TB16H3 |
More data for this Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50183730
(CHEMBL380895 | N-(4-(2-(hydroxyamino)-2-oxoethyl)-...)Show SMILES CN1CCC(CC(=O)NO)(CC1)NC(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 Show InChI InChI=1S/C26H30N4O4/c1-18-15-20(22-5-3-4-6-23(22)27-18)17-34-21-9-7-19(8-10-21)25(32)28-26(16-24(31)29-33)11-13-30(2)14-12-26/h3-10,15,33H,11-14,16-17H2,1-2H3,(H,28,32)(H,29,31) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >4.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding affinity to MMP1 |
Bioorg Med Chem Lett 16: 2699-704 (2006)
Article DOI: 10.1016/j.bmcl.2006.02.015 BindingDB Entry DOI: 10.7270/Q2TB16H3 |
More data for this Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50183730
(CHEMBL380895 | N-(4-(2-(hydroxyamino)-2-oxoethyl)-...)Show SMILES CN1CCC(CC(=O)NO)(CC1)NC(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 Show InChI InChI=1S/C26H30N4O4/c1-18-15-20(22-5-3-4-6-23(22)27-18)17-34-21-9-7-19(8-10-21)25(32)28-26(16-24(31)29-33)11-13-30(2)14-12-26/h3-10,15,33H,11-14,16-17H2,1-2H3,(H,28,32)(H,29,31) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >5.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding affinity to MMP13 |
Bioorg Med Chem Lett 16: 2699-704 (2006)
Article DOI: 10.1016/j.bmcl.2006.02.015 BindingDB Entry DOI: 10.7270/Q2TB16H3 |
More data for this Ligand-Target Pair | |
ADAM17
(Sus scrofa (pig)) | BDBM50183730
(CHEMBL380895 | N-(4-(2-(hydroxyamino)-2-oxoethyl)-...)Show SMILES CN1CCC(CC(=O)NO)(CC1)NC(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 Show InChI InChI=1S/C26H30N4O4/c1-18-15-20(22-5-3-4-6-23(22)27-18)17-34-21-9-7-19(8-10-21)25(32)28-26(16-24(31)29-33)11-13-30(2)14-12-26/h3-10,15,33H,11-14,16-17H2,1-2H3,(H,28,32)(H,29,31) | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of porcine TACE |
Bioorg Med Chem Lett 16: 2699-704 (2006)
Article DOI: 10.1016/j.bmcl.2006.02.015 BindingDB Entry DOI: 10.7270/Q2TB16H3 |
More data for this Ligand-Target Pair | |
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human)) | BDBM50183730
(CHEMBL380895 | N-(4-(2-(hydroxyamino)-2-oxoethyl)-...)Show SMILES CN1CCC(CC(=O)NO)(CC1)NC(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 Show InChI InChI=1S/C26H30N4O4/c1-18-15-20(22-5-3-4-6-23(22)27-18)17-34-21-9-7-19(8-10-21)25(32)28-26(16-24(31)29-33)11-13-30(2)14-12-26/h3-10,15,33H,11-14,16-17H2,1-2H3,(H,28,32)(H,29,31) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 109 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of LPS-stimulated TNFalpha production in human whole blood |
Bioorg Med Chem Lett 16: 2699-704 (2006)
Article DOI: 10.1016/j.bmcl.2006.02.015 BindingDB Entry DOI: 10.7270/Q2TB16H3 |
More data for this Ligand-Target Pair | |