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SMILES: CCCCN(C)C(=O)[C@@H](NC(=O)CSc1ccc(NC(=O)c2ccccc2-c2ccc(cc2)C(F)(F)F)cc1)c1ccccc1

InChI Key: InChIKey=UFQRDPLMULSBEJ-YTTGMZPUSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184163   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Microsomal triglyceride transfer protein large subunit


(Homo sapiens (Human))		BDBM50184163
PNG
(4'-trifluoromethyl-biphenyl-2-carboxylic acid [4-(...)
Show SMILES CCCCN(C)C(=O)[C@@H](NC(=O)CSc1ccc(NC(=O)c2ccccc2-c2ccc(cc2)C(F)(F)F)cc1)c1ccccc1
Show InChI InChI=1S/C35H34F3N3O3S/c1-3-4-22-41(2)34(44)32(25-10-6-5-7-11-25)40-31(42)23-45-28-20-18-27(19-21-28)39-33(43)30-13-9-8-12-29(30)24-14-16-26(17-15-24)35(36,37)38/h5-21,32H,3-4,22-23H2,1-2H3,(H,39,43)(H,40,42)/t32-/m0/s1
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Article
PubMed
n/an/a 17.3n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of MTP in canine liver microsomes

Bioorg Med Chem Lett 16: 3039-42 (2006)


Article DOI: 10.1016/j.bmcl.2006.02.058
BindingDB Entry DOI: 10.7270/Q2D21X68
More data for this
Ligand-Target Pair