BDBM50184668 CHEMBL377695::[4-(4,4''-dichloro-[1,1';3',1'']terphenyl-5'-ylmethoxy)-2-methyl-phenoxy]-acetic acid
SMILES: Cc1cc(OCc2cc(cc(c2)-c2ccc(Cl)cc2)-c2ccc(Cl)cc2)ccc1OCC(O)=O
InChI Key: InChIKey=BHBKYCXEDQWJEZ-UHFFFAOYSA-N
Data: 3 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human)) | BDBM50184668 (CHEMBL377695 | [4-(4,4''-dichloro-[1,1';3',1'']ter...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 110 | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Effect on human PPARdelta transactivation in 293T cells | Bioorg Med Chem Lett 16: 2969-73 (2006) Article DOI: 10.1016/j.bmcl.2006.02.079 BindingDB Entry DOI: 10.7270/Q2XW4JDG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human)) | BDBM50184668 (CHEMBL377695 | [4-(4,4''-dichloro-[1,1';3',1'']ter...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Effect on human PPARalpha transactivation in 293T cells | Bioorg Med Chem Lett 16: 2969-73 (2006) Article DOI: 10.1016/j.bmcl.2006.02.079 BindingDB Entry DOI: 10.7270/Q2XW4JDG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM50184668 (CHEMBL377695 | [4-(4,4''-dichloro-[1,1';3',1'']ter...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Effect on human PPARgamma transactivation in 293T cells | Bioorg Med Chem Lett 16: 2969-73 (2006) Article DOI: 10.1016/j.bmcl.2006.02.079 BindingDB Entry DOI: 10.7270/Q2XW4JDG | |||||||||||
More data for this Ligand-Target Pair |