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SMILES: CS(=O)(=O)N1CCC(CC1)C(=O)N(CCCN1CCC(CC1)NC(=O)c1ccc(F)cc1)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=NTMGUIDGOILDRZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50185962   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50185962
PNG
(CHEMBL210327 | N-(3,4-dichlorophenyl)-N-(3-{4-[(4-...)
Show SMILES CS(=O)(=O)N1CCC(CC1)C(=O)N(CCCN1CCC(CC1)NC(=O)c1ccc(F)cc1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C28H35Cl2FN4O4S/c1-40(38,39)34-17-9-21(10-18-34)28(37)35(24-7-8-25(29)26(30)19-24)14-2-13-33-15-11-23(12-16-33)32-27(36)20-3-5-22(31)6-4-20/h3-8,19,21,23H,2,9-18H2,1H3,(H,32,36)
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Similars
Article
PubMed
n/an/a 730n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

Curated by ChEMBL


Assay Description
Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cells

J Med Chem 49: 2784-93 (2006)


Article DOI: 10.1021/jm051034q
BindingDB Entry DOI: 10.7270/Q2ZK5G8F
More data for this
Ligand-Target Pair