BDBM50186291 2-isopropyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydroisoquinoline::CHEMBL208650
SMILES: CC(C)N1CCc2ccc(OCCCN3CCCCC3)cc2C1
InChI Key: InChIKey=BXVVIFARYFEXEA-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50186291 (2-isopropyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor | Bioorg Med Chem Lett 16: 3415-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Rattus norvegicus (rat)) | BDBM50186291 (2-isopropyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.890 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptor | Bioorg Med Chem Lett 16: 3415-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 | |||||||||||
More data for this Ligand-Target Pair |