BDBM50186295 2-(methylsulfonyl)-7-(3-(piperidin-1-yl)propoxy)-2,3,4,5-tetrahydro-1H-benzo[c]azepine::CHEMBL207062
SMILES: CS(=O)(=O)N1CCCc2cc(OCCCN3CCCCC3)ccc2C1
InChI Key: InChIKey=KEECVFYIAQVONM-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50186295 (2-(methylsulfonyl)-7-(3-(piperidin-1-yl)propoxy)-2...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor | Bioorg Med Chem Lett 16: 3415-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Rattus norvegicus (rat)) | BDBM50186295 (2-(methylsulfonyl)-7-(3-(piperidin-1-yl)propoxy)-2...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 70.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptor | Bioorg Med Chem Lett 16: 3415-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 | |||||||||||
More data for this Ligand-Target Pair |