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BDBM50186297 CHEMBL209099::N-isopropyl-7-(3-(piperidin-1-yl)propoxy)-4,5-dihydro-1H-benzo[c]azepine-2(3H)-carboxamide

SMILES: CC(C)NC(=O)N1CCCc2cc(OCCCN3CCCCC3)ccc2C1

InChI Key: InChIKey=ZSWBEXROVVAQGI-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186297   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50186297
PNG
(CHEMBL209099 | N-isopropyl-7-(3-(piperidin-1-yl)pr...)
Show SMILES CC(C)NC(=O)N1CCCc2cc(OCCCN3CCCCC3)ccc2C1
Show InChI InChI=1S/C22H35N3O2/c1-18(2)23-22(26)25-14-6-8-19-16-21(10-9-20(19)17-25)27-15-7-13-24-11-4-3-5-12-24/h9-10,16,18H,3-8,11-15,17H2,1-2H3,(H,23,26)
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KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
17.1n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor


Bioorg Med Chem Lett 16: 3415-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.04.004
BindingDB Entry DOI: 10.7270/Q2WM1D07
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50186297
PNG
(CHEMBL209099 | N-isopropyl-7-(3-(piperidin-1-yl)pr...)
Show SMILES CC(C)NC(=O)N1CCCc2cc(OCCCN3CCCCC3)ccc2C1
Show InChI InChI=1S/C22H35N3O2/c1-18(2)23-22(26)25-14-6-8-19-16-21(10-9-20(19)17-25)27-15-7-13-24-11-4-3-5-12-24/h9-10,16,18H,3-8,11-15,17H2,1-2H3,(H,23,26)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
32.5n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptor


Bioorg Med Chem Lett 16: 3415-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.04.004
BindingDB Entry DOI: 10.7270/Q2WM1D07
More data for this
Ligand-Target Pair