BDBM50186308 2-ethyl-8-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydroisoquinoline::CHEMBL209098

SMILES: CCN1CCc2cccc(OCCCN3CCCCC3)c2C1

InChI Key: InChIKey=KDDRLLCATKACPK-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186308   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50186308 (2-ethyl-8-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetr...) Show SMILES CCN1CCc2cccc(OCCCN3CCCCC3)c2C1 Show InChI InChI=1S/C19H30N2O/c1-2-20-14-10-17-8-6-9-19(18(17)16-20)22-15-7-13-21-11-4-3-5-12-21/h6,8-9H,2-5,7,10-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	95	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
BIOPROJET-BIOTECH Curated by ChEMBL					Assay Description Binding affinity to histamine H3 receptor (unknown origin)				Bioorg Med Chem 21: 4526-9 (2013) Article DOI: 10.1016/j.bmc.2013.05.035 BindingDB Entry DOI: 10.7270/Q2J9699Q
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50186308 (2-ethyl-8-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetr...) Show SMILES CCN1CCc2cccc(OCCCN3CCCCC3)c2C1 Show InChI InChI=1S/C19H30N2O/c1-2-20-14-10-17-8-6-9-19(18(17)16-20)22-15-7-13-21-11-4-3-5-12-21/h6,8-9H,2-5,7,10-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	95.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor				Bioorg Med Chem Lett 16: 3415-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07
					More data for this Ligand-Target Pair