null

SMILES: Fc1cc2[nH]c(CNC(C3CCN(CC3)C(=O)OCc3ccccc3)c3ccc(cc3)-c3cccc(c3)C#N)nc2cc1Cl

InChI Key: InChIKey=JFMIBDAAZFALFW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186775   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50186775 (4-[[(6-chloro-5-fluoro-1H-benzoimidazol-2-ylmethyl...) Show SMILES Fc1cc2[nH]c(CNC(C3CCN(CC3)C(=O)OCc3ccccc3)c3ccc(cc3)-c3cccc(c3)C#N)nc2cc1Cl Show InChI InChI=1S/C35H31ClFN5O2/c36-29-18-31-32(19-30(29)37)41-33(40-31)21-39-34(26-11-9-25(10-12-26)28-8-4-7-24(17-28)20-38)27-13-15-42(16-14-27)35(43)44-22-23-5-2-1-3-6-23/h1-12,17-19,27,34,39H,13-16,21-22H2,(H,40,41)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human MCHR1 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assay				Bioorg Med Chem Lett 16: 3668-73 (2006) Article DOI: 10.1016/j.bmcl.2006.04.061 BindingDB Entry DOI: 10.7270/Q2251HT9
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 2 (Homo sapiens (Human))	BDBM50186775 (4-[[(6-chloro-5-fluoro-1H-benzoimidazol-2-ylmethyl...) Show SMILES Fc1cc2[nH]c(CNC(C3CCN(CC3)C(=O)OCc3ccccc3)c3ccc(cc3)-c3cccc(c3)C#N)nc2cc1Cl Show InChI InChI=1S/C35H31ClFN5O2/c36-29-18-31-32(19-30(29)37)41-33(40-31)21-39-34(26-11-9-25(10-12-26)28-8-4-7-24(17-28)20-38)27-13-15-42(16-14-27)35(43)44-22-23-5-2-1-3-6-23/h1-12,17-19,27,34,39H,13-16,21-22H2,(H,40,41)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human MCHR2 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assay				Bioorg Med Chem Lett 16: 3668-73 (2006) Article DOI: 10.1016/j.bmcl.2006.04.061 BindingDB Entry DOI: 10.7270/Q2251HT9
					More data for this Ligand-Target Pair