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BDBM50186870 CHEMBL208953::N-{(R)-1-(4-chloro-benzyl)-2-[4-(4-ethyl-1-methyl-piperidin-4-yl)-piperazin-1-yl]-2-oxo-ethyl}-2-(2,3-dihydro-1H-isoindol-1-yl)-acetamide trifluoroacetic acid

SMILES: CCC1(CCN(C)CC1)N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)CC1NCc2ccccc12

InChI Key: InChIKey=RCLFGGUMFZITKQ-PLYLYKGUSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50186870   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))		BDBM50186870
PNG
(CHEMBL208953 | N-{(R)-1-(4-chloro-benzyl)-2-[4-(4-...)
Show SMILES CCC1(CCN(C)CC1)N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)CC1NCc2ccccc12
Show InChI InChI=1S/C31H42ClN5O2/c1-3-31(12-14-35(2)15-13-31)37-18-16-36(17-19-37)30(39)28(20-23-8-10-25(32)11-9-23)34-29(38)21-27-26-7-5-4-6-24(26)22-33-27/h4-11,27-28,33H,3,12-22H2,1-2H3,(H,34,38)/t27?,28-/m1/s1
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KEGG

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PC cid
PC sid
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Similars
Article
PubMed
 370n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-alpha-MSH from human MC4 receptor transfected in HEK293 cells

Bioorg Med Chem Lett 16: 3843-6 (2006)


Article DOI: 10.1016/j.bmcl.2006.04.016
BindingDB Entry DOI: 10.7270/Q2SQ900D
More data for this
Ligand-Target Pair