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BDBM50186874 CHEMBL376999::N-{(R)-1-(4-chloro-benzyl)-2-[4-(4-isobutyl-1-methyl-piperidin-4-yl)-piperazin-1-yl]-2-oxo-ethyl}-2-(2,3-dihydro-1H-isoindol-1-yl)-acetamide trifluoroacetic id

SMILES: CC(C)CC1(CCN(C)CC1)N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)CC1NCc2ccccc12

InChI Key: InChIKey=LWBXLZBGWUEHNG-BDCODIICSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50186874   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))		BDBM50186874
PNG
(CHEMBL376999 | N-{(R)-1-(4-chloro-benzyl)-2-[4-(4-...)
Show SMILES CC(C)CC1(CCN(C)CC1)N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)CC1NCc2ccccc12
Show InChI InChI=1S/C33H46ClN5O2/c1-24(2)22-33(12-14-37(3)15-13-33)39-18-16-38(17-19-39)32(41)30(20-25-8-10-27(34)11-9-25)36-31(40)21-29-28-7-5-4-6-26(28)23-35-29/h4-11,24,29-30,35H,12-23H2,1-3H3,(H,36,40)/t29?,30-/m1/s1
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KEGG

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Similars
Article
PubMed
 13n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-alpha-MSH from human MC4 receptor transfected in HEK293 cells

Bioorg Med Chem Lett 16: 3843-6 (2006)


Article DOI: 10.1016/j.bmcl.2006.04.016
BindingDB Entry DOI: 10.7270/Q2SQ900D
More data for this
Ligand-Target Pair