BDBM50186929 3-(4-(5-(3-cyano-4-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)phenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid::CHEMBL210942

SMILES: Cc1cc(CCC(O)=O)ccc1-c1noc(n1)-c1ccc(OC(C(F)(F)F)C(F)(F)F)c(c1)C#N

InChI Key: InChIKey=HTJYQFNFGMOXCX-UHFFFAOYSA-N

Data: 5 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50186929   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM50186929 (3-(4-(5-(3-cyano-4-(1,1,1,3,3,3-hexafluoropropan-2...) Show SMILES Cc1cc(CCC(O)=O)ccc1-c1noc(n1)-c1ccc(OC(C(F)(F)F)C(F)(F)F)c(c1)C#N Show InChI InChI=1S/C22H15F6N3O4/c1-11-8-12(3-7-17(32)33)2-5-15(11)18-30-19(35-31-18)13-4-6-16(14(9-13)10-29)34-20(21(23,24)25)22(26,27)28/h2,4-6,8-9,20H,3,7H2,1H3,(H,32,33)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	340	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at S1P3 receptor expressed in CHO cells measured as S1P-induced [35S]GTPgammaS uptake				Bioorg Med Chem Lett 16: 3679-83 (2006) Article DOI: 10.1016/j.bmcl.2006.04.084 BindingDB Entry DOI: 10.7270/Q2J67GJ8
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 2 (Homo sapiens (Human))	BDBM50186929 (3-(4-(5-(3-cyano-4-(1,1,1,3,3,3-hexafluoropropan-2...) Show SMILES Cc1cc(CCC(O)=O)ccc1-c1noc(n1)-c1ccc(OC(C(F)(F)F)C(F)(F)F)c(c1)C#N Show InChI InChI=1S/C22H15F6N3O4/c1-11-8-12(3-7-17(32)33)2-5-15(11)18-30-19(35-31-18)13-4-6-16(14(9-13)10-29)34-20(21(23,24)25)22(26,27)28/h2,4-6,8-9,20H,3,7H2,1H3,(H,32,33)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Activity at S1P2 receptor expressed in CHO cells measured as S1P-induced [35S]GTPgammaS uptake				Bioorg Med Chem Lett 16: 3679-83 (2006) Article DOI: 10.1016/j.bmcl.2006.04.084 BindingDB Entry DOI: 10.7270/Q2J67GJ8
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 4 (Homo sapiens (Human))	BDBM50186929 (3-(4-(5-(3-cyano-4-(1,1,1,3,3,3-hexafluoropropan-2...) Show SMILES Cc1cc(CCC(O)=O)ccc1-c1noc(n1)-c1ccc(OC(C(F)(F)F)C(F)(F)F)c(c1)C#N Show InChI InChI=1S/C22H15F6N3O4/c1-11-8-12(3-7-17(32)33)2-5-15(11)18-30-19(35-31-18)13-4-6-16(14(9-13)10-29)34-20(21(23,24)25)22(26,27)28/h2,4-6,8-9,20H,3,7H2,1H3,(H,32,33)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Activity at S1P4 receptor expressed in CHO cells measured as S1P-induced [35S]GTPgammaS uptake				Bioorg Med Chem Lett 16: 3679-83 (2006) Article DOI: 10.1016/j.bmcl.2006.04.084 BindingDB Entry DOI: 10.7270/Q2J67GJ8
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 5 (Homo sapiens (Human))	BDBM50186929 (3-(4-(5-(3-cyano-4-(1,1,1,3,3,3-hexafluoropropan-2...) Show SMILES Cc1cc(CCC(O)=O)ccc1-c1noc(n1)-c1ccc(OC(C(F)(F)F)C(F)(F)F)c(c1)C#N Show InChI InChI=1S/C22H15F6N3O4/c1-11-8-12(3-7-17(32)33)2-5-15(11)18-30-19(35-31-18)13-4-6-16(14(9-13)10-29)34-20(21(23,24)25)22(26,27)28/h2,4-6,8-9,20H,3,7H2,1H3,(H,32,33)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.700	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at S1P5 receptor expressed in CHO cells measured as S1P-induced [35S]GTPgammaS uptake				Bioorg Med Chem Lett 16: 3679-83 (2006) Article DOI: 10.1016/j.bmcl.2006.04.084 BindingDB Entry DOI: 10.7270/Q2J67GJ8
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50186929 (3-(4-(5-(3-cyano-4-(1,1,1,3,3,3-hexafluoropropan-2...) Show SMILES Cc1cc(CCC(O)=O)ccc1-c1noc(n1)-c1ccc(OC(C(F)(F)F)C(F)(F)F)c(c1)C#N Show InChI InChI=1S/C22H15F6N3O4/c1-11-8-12(3-7-17(32)33)2-5-15(11)18-30-19(35-31-18)13-4-6-16(14(9-13)10-29)34-20(21(23,24)25)22(26,27)28/h2,4-6,8-9,20H,3,7H2,1H3,(H,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTPgammaS uptake				Bioorg Med Chem Lett 16: 3679-83 (2006) Article DOI: 10.1016/j.bmcl.2006.04.084 BindingDB Entry DOI: 10.7270/Q2J67GJ8
					More data for this Ligand-Target Pair