BDBM50187059 1-(3-methoxyphenyl)-3-(5-(pyridin-4-yl)-1,3,4-thiadiazol-2-yl)urea::CHEMBL377430

SMILES: COc1cccc(NC(=O)Nc2nnc(s2)-c2ccncc2)c1

InChI Key: InChIKey=ABANLXYNSSVWDG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50187059   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual-specificity tyrosine-phosphorylation regulated kinase 1A (Mus musculus)	BDBM50187059 (1-(3-methoxyphenyl)-3-(5-(pyridin-4-yl)-1,3,4-thia...) Show SMILES COc1cccc(NC(=O)Nc2nnc(s2)-c2ccncc2)c1 Show InChI InChI=1S/C15H13N5O2S/c1-22-12-4-2-3-11(9-12)17-14(21)18-15-20-19-13(23-15)10-5-7-16-8-6-10/h2-9H,1H3,(H2,17,18,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Research Center IDRTech Inc. Curated by ChEMBL					Assay Description Inhibition of mouse Dyrk1A autophosphorylation in HEk293 cells				Bioorg Med Chem Lett 16: 3772-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.042 BindingDB Entry DOI: 10.7270/Q2K938BX
					More data for this Ligand-Target Pair