BDBM50187061 3-ethyl 6-methyl 4-(3-acetylphenylamino)quinoline-3,6-dicarboxylate::CHEMBL213905

SMILES: CCOC(=O)c1cnc2ccc(cc2c1Nc1cccc(c1)C(C)=O)C(=O)OC

InChI Key: InChIKey=WKUCRZYWCJQVMS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50187061   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual-specificity tyrosine-phosphorylation regulated kinase 1A (Mus musculus)	BDBM50187061 (3-ethyl 6-methyl 4-(3-acetylphenylamino)quinoline-...) Show SMILES CCOC(=O)c1cnc2ccc(cc2c1Nc1cccc(c1)C(C)=O)C(=O)OC Show InChI InChI=1S/C22H20N2O5/c1-4-29-22(27)18-12-23-19-9-8-15(21(26)28-3)11-17(19)20(18)24-16-7-5-6-14(10-16)13(2)25/h5-12H,4H2,1-3H3,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Research Center IDRTech Inc. Curated by ChEMBL					Assay Description Inhibition of mouse Dyrk1A autophosphorylation in HEk293 cells				Bioorg Med Chem Lett 16: 3772-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.042 BindingDB Entry DOI: 10.7270/Q2K938BX
					More data for this Ligand-Target Pair