Found 5 hits for monomerid = 50187225 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Human immunodeficiency virus type 1 reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50187225
((S)-1-(2-amino-4-chloro-5-methylphenylsulfonyl)pyr...)Show InChI InChI=1S/C12H15ClN2O4S/c1-7-5-11(9(14)6-8(7)13)20(18,19)15-4-2-3-10(15)12(16)17/h5-6,10H,2-4,14H2,1H3,(H,16,17)/t10-/m0/s1 | PDB MMDB
UniProtKB/TrEMBL
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of HIV reverse transcriptase |
J Med Chem 49: 3052-5 (2006)
Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517 |
More data for this Ligand-Target Pair | |
Hepatitis C virus serine protease, NS3/NS4A
(Hepatitis C virus) | BDBM50187225
((S)-1-(2-amino-4-chloro-5-methylphenylsulfonyl)pyr...)Show InChI InChI=1S/C12H15ClN2O4S/c1-7-5-11(9(14)6-8(7)13)20(18,19)15-4-2-3-10(15)12(16)17/h5-6,10H,2-4,14H2,1H3,(H,16,17)/t10-/m0/s1 | PDB MMDB
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | >7.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of HCV helicase |
J Med Chem 49: 3052-5 (2006)
Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517 |
More data for this Ligand-Target Pair | |
DNA polymerase (alpha/delta/epsilon)
(Homo sapiens (Human)) | BDBM50187225
((S)-1-(2-amino-4-chloro-5-methylphenylsulfonyl)pyr...)Show InChI InChI=1S/C12H15ClN2O4S/c1-7-5-11(9(14)6-8(7)13)20(18,19)15-4-2-3-10(15)12(16)17/h5-6,10H,2-4,14H2,1H3,(H,16,17)/t10-/m0/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of calf thymus polymerase alpha |
J Med Chem 49: 3052-5 (2006)
Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517 |
More data for this Ligand-Target Pair | |
DNA polymerase beta
(Homo sapiens (Human)) | BDBM50187225
((S)-1-(2-amino-4-chloro-5-methylphenylsulfonyl)pyr...)Show InChI InChI=1S/C12H15ClN2O4S/c1-7-5-11(9(14)6-8(7)13)20(18,19)15-4-2-3-10(15)12(16)17/h5-6,10H,2-4,14H2,1H3,(H,16,17)/t10-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of human polymerase beta |
J Med Chem 49: 3052-5 (2006)
Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517 |
More data for this Ligand-Target Pair | |
Hepatitis C virus NS5B RNA-dependent RNA polymerase
(Hepatitis C virus) | BDBM50187225
((S)-1-(2-amino-4-chloro-5-methylphenylsulfonyl)pyr...)Show InChI InChI=1S/C12H15ClN2O4S/c1-7-5-11(9(14)6-8(7)13)20(18,19)15-4-2-3-10(15)12(16)17/h5-6,10H,2-4,14H2,1H3,(H,16,17)/t10-/m0/s1 | UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of HCV NS5B RNA dependent RNA polymerase |
J Med Chem 49: 3052-5 (2006)
Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517 |
More data for this Ligand-Target Pair | |