BDBM50187282 (2R,5S)-1-(2-(1-(2-hydroxyethyl)cyclopentylamino)acetyl)pyrrolidine-2,5-dicarbonitrile::CHEMBL209934

SMILES: OCCC1(CCCC1)NCC(=O)N1[C@@H](CC[C@@H]1C#N)C#N

InChI Key: InChIKey=XMGOKUGTMOXDAB-BETUJISGSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50187282   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50187282 ((2R,5S)-1-(2-(1-(2-hydroxyethyl)cyclopentylamino)a...) Show SMILES OCCC1(CCCC1)NCC(=O)N1[C@@H](CC[C@@H]1C#N)C#N Show InChI InChI=1S/C15H22N4O2/c16-9-12-3-4-13(10-17)19(12)14(21)11-18-15(7-8-20)5-1-2-6-15/h12-13,18,20H,1-8,11H2/t12-,13+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP4				J Med Chem 49: 3068-76 (2006) Article DOI: 10.1021/jm0600085 BindingDB Entry DOI: 10.7270/Q2BG2NM7
					More data for this Ligand-Target Pair