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SMILES: Clc1ccccc1CC(N1CCNCC1)c1cncs1

InChI Key: InChIKey=XEWUKTSZOJWBEW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50188118   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50188118 (1-(2-(2-chlorophenyl)-1-(thiazol-5-yl)ethyl)pipera...) Show SMILES Clc1ccccc1CC(N1CCNCC1)c1cncs1 Show InChI InChI=1S/C15H18ClN3S/c16-13-4-2-1-3-12(13)9-14(15-10-18-11-20-15)19-7-5-17-6-8-19/h1-4,10-11,14,17H,5-9H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]NA reuptake at NA transporter in HEK293 cells				Bioorg Med Chem Lett 16: 4349-53 (2006) Article DOI: 10.1016/j.bmcl.2006.05.049 BindingDB Entry DOI: 10.7270/Q2SQ916H
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50188118 (1-(2-(2-chlorophenyl)-1-(thiazol-5-yl)ethyl)pipera...) Show SMILES Clc1ccccc1CC(N1CCNCC1)c1cncs1 Show InChI InChI=1S/C15H18ClN3S/c16-13-4-2-1-3-12(13)9-14(15-10-18-11-20-15)19-7-5-17-6-8-19/h1-4,10-11,14,17H,5-9H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]5-HT reuptake at 5HT transporter in HEK293 cells				Bioorg Med Chem Lett 16: 4349-53 (2006) Article DOI: 10.1016/j.bmcl.2006.05.049 BindingDB Entry DOI: 10.7270/Q2SQ916H
					More data for this Ligand-Target Pair