BDBM50188255 2-(3-chloro-4-(5-methyl-4-((2-(2-nitrophenoxy)ethyl)carbamoyl)isoxazol-3-yl)phenyl)acetic acid::CHEMBL378881

SMILES: Cc1onc(c1C(=O)NCCOc1ccccc1[N+]([O-])=O)-c1ccc(CC(O)=O)cc1Cl

InChI Key: InChIKey=ITUIKSCIIWOHND-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50188255   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50188255 (2-(3-chloro-4-(5-methyl-4-((2-(2-nitrophenoxy)ethy...) Show SMILES Cc1onc(c1C(=O)NCCOc1ccccc1[N+]([O-])=O)-c1ccc(CC(O)=O)cc1Cl Show InChI InChI=1S/C21H18ClN3O7/c1-12-19(20(24-32-12)14-7-6-13(10-15(14)22)11-18(26)27)21(28)23-8-9-31-17-5-3-2-4-16(17)25(29)30/h2-7,10H,8-9,11H2,1H3,(H,23,28)(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at PPARgamma by transactivation assay				Bioorg Med Chem Lett 16: 4376-80 (2006) Article DOI: 10.1016/j.bmcl.2006.05.055 BindingDB Entry DOI: 10.7270/Q2V987PC
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50188255 (2-(3-chloro-4-(5-methyl-4-((2-(2-nitrophenoxy)ethy...) Show SMILES Cc1onc(c1C(=O)NCCOc1ccccc1[N+]([O-])=O)-c1ccc(CC(O)=O)cc1Cl Show InChI InChI=1S/C21H18ClN3O7/c1-12-19(20(24-32-12)14-7-6-13(10-15(14)22)11-18(26)27)21(28)23-8-9-31-17-5-3-2-4-16(17)25(29)30/h2-7,10H,8-9,11H2,1H3,(H,23,28)(H,26,27)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at PPARalpha by transactivation assay				Bioorg Med Chem Lett 16: 4376-80 (2006) Article DOI: 10.1016/j.bmcl.2006.05.055 BindingDB Entry DOI: 10.7270/Q2V987PC
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50188255 (2-(3-chloro-4-(5-methyl-4-((2-(2-nitrophenoxy)ethy...) Show SMILES Cc1onc(c1C(=O)NCCOc1ccccc1[N+]([O-])=O)-c1ccc(CC(O)=O)cc1Cl Show InChI InChI=1S/C21H18ClN3O7/c1-12-19(20(24-32-12)14-7-6-13(10-15(14)22)11-18(26)27)21(28)23-8-9-31-17-5-3-2-4-16(17)25(29)30/h2-7,10H,8-9,11H2,1H3,(H,23,28)(H,26,27)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at PPARdelta by transactivation assay				Bioorg Med Chem Lett 16: 4376-80 (2006) Article DOI: 10.1016/j.bmcl.2006.05.055 BindingDB Entry DOI: 10.7270/Q2V987PC
					More data for this Ligand-Target Pair