BDBM50188256 2-(3-chloro-4-(4-(4-(2,4-dichlorophenoxy)butanoyl)-5-phenylisoxazol-3-yl)phenyl)acetic acid::CHEMBL215605

SMILES: OC(=O)Cc1ccc(-c2noc(c2C(=O)CCCOc2ccc(Cl)cc2Cl)-c2ccccc2)c(Cl)c1

InChI Key: InChIKey=VINJHESJAFNNRA-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50188256   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50188256 (2-(3-chloro-4-(4-(4-(2,4-dichlorophenoxy)butanoyl)...) Show SMILES OC(=O)Cc1ccc(-c2noc(c2C(=O)CCCOc2ccc(Cl)cc2Cl)-c2ccccc2)c(Cl)c1 Show InChI InChI=1S/C27H20Cl3NO5/c28-18-9-11-23(21(30)15-18)35-12-4-7-22(32)25-26(31-36-27(25)17-5-2-1-3-6-17)19-10-8-16(13-20(19)29)14-24(33)34/h1-3,5-6,8-11,13,15H,4,7,12,14H2,(H,33,34)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at PPARdelta by transactivation assay				Bioorg Med Chem Lett 16: 4376-80 (2006) Article DOI: 10.1016/j.bmcl.2006.05.055 BindingDB Entry DOI: 10.7270/Q2V987PC
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50188256 (2-(3-chloro-4-(4-(4-(2,4-dichlorophenoxy)butanoyl)...) Show SMILES OC(=O)Cc1ccc(-c2noc(c2C(=O)CCCOc2ccc(Cl)cc2Cl)-c2ccccc2)c(Cl)c1 Show InChI InChI=1S/C27H20Cl3NO5/c28-18-9-11-23(21(30)15-18)35-12-4-7-22(32)25-26(31-36-27(25)17-5-2-1-3-6-17)19-10-8-16(13-20(19)29)14-24(33)34/h1-3,5-6,8-11,13,15H,4,7,12,14H2,(H,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at PPARgamma by transactivation assay				Bioorg Med Chem Lett 16: 4376-80 (2006) Article DOI: 10.1016/j.bmcl.2006.05.055 BindingDB Entry DOI: 10.7270/Q2V987PC
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50188256 (2-(3-chloro-4-(4-(4-(2,4-dichlorophenoxy)butanoyl)...) Show SMILES OC(=O)Cc1ccc(-c2noc(c2C(=O)CCCOc2ccc(Cl)cc2Cl)-c2ccccc2)c(Cl)c1 Show InChI InChI=1S/C27H20Cl3NO5/c28-18-9-11-23(21(30)15-18)35-12-4-7-22(32)25-26(31-36-27(25)17-5-2-1-3-6-17)19-10-8-16(13-20(19)29)14-24(33)34/h1-3,5-6,8-11,13,15H,4,7,12,14H2,(H,33,34)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at PPARalpha by transactivation assay				Bioorg Med Chem Lett 16: 4376-80 (2006) Article DOI: 10.1016/j.bmcl.2006.05.055 BindingDB Entry DOI: 10.7270/Q2V987PC
					More data for this Ligand-Target Pair