BDBM50188260 2-(4-(4-((2-(2,4-dichlorophenoxy)ethyl)carbamoyl)-5-ethylisoxazol-3-yl)-3-chlorophenyl)acetic acid::CHEMBL380232

SMILES: CCc1onc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccc(CC(O)=O)cc1Cl

InChI Key: InChIKey=AYBCPAUHDJRCLO-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50188260   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50188260 (2-(4-(4-((2-(2,4-dichlorophenoxy)ethyl)carbamoyl)-...) Show SMILES CCc1onc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccc(CC(O)=O)cc1Cl Show InChI InChI=1S/C22H19Cl3N2O5/c1-2-17-20(22(30)26-7-8-31-18-6-4-13(23)11-16(18)25)21(27-32-17)14-5-3-12(9-15(14)24)10-19(28)29/h3-6,9,11H,2,7-8,10H2,1H3,(H,26,30)(H,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at PPARalpha by transactivation assay				Bioorg Med Chem Lett 16: 4376-80 (2006) Article DOI: 10.1016/j.bmcl.2006.05.055 BindingDB Entry DOI: 10.7270/Q2V987PC
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50188260 (2-(4-(4-((2-(2,4-dichlorophenoxy)ethyl)carbamoyl)-...) Show SMILES CCc1onc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccc(CC(O)=O)cc1Cl Show InChI InChI=1S/C22H19Cl3N2O5/c1-2-17-20(22(30)26-7-8-31-18-6-4-13(23)11-16(18)25)21(27-32-17)14-5-3-12(9-15(14)24)10-19(28)29/h3-6,9,11H,2,7-8,10H2,1H3,(H,26,30)(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at PPARgamma by transactivation assay				Bioorg Med Chem Lett 16: 4376-80 (2006) Article DOI: 10.1016/j.bmcl.2006.05.055 BindingDB Entry DOI: 10.7270/Q2V987PC
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50188260 (2-(4-(4-((2-(2,4-dichlorophenoxy)ethyl)carbamoyl)-...) Show SMILES CCc1onc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccc(CC(O)=O)cc1Cl Show InChI InChI=1S/C22H19Cl3N2O5/c1-2-17-20(22(30)26-7-8-31-18-6-4-13(23)11-16(18)25)21(27-32-17)14-5-3-12(9-15(14)24)10-19(28)29/h3-6,9,11H,2,7-8,10H2,1H3,(H,26,30)(H,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at PPARdelta by transactivation assay				Bioorg Med Chem Lett 16: 4376-80 (2006) Article DOI: 10.1016/j.bmcl.2006.05.055 BindingDB Entry DOI: 10.7270/Q2V987PC
					More data for this Ligand-Target Pair