BDBM50188261 2-(3-chloro-4-(5-methyl-4-((2-(4-(trifluoromethyl)phenoxy)ethyl)carbamoyl)isoxazol-3-yl)phenyl)acetic acid::CHEMBL209595

SMILES: Cc1onc(c1C(=O)NCCOc1ccc(cc1)C(F)(F)F)-c1ccc(CC(O)=O)cc1Cl

InChI Key: InChIKey=LGBXSTFVDYSEBB-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50188261   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50188261 (2-(3-chloro-4-(5-methyl-4-((2-(4-(trifluoromethyl)...) Show SMILES Cc1onc(c1C(=O)NCCOc1ccc(cc1)C(F)(F)F)-c1ccc(CC(O)=O)cc1Cl Show InChI InChI=1S/C22H18ClF3N2O5/c1-12-19(20(28-33-12)16-7-2-13(10-17(16)23)11-18(29)30)21(31)27-8-9-32-15-5-3-14(4-6-15)22(24,25)26/h2-7,10H,8-9,11H2,1H3,(H,27,31)(H,29,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at PPARdelta by transactivation assay				Bioorg Med Chem Lett 16: 4376-80 (2006) Article DOI: 10.1016/j.bmcl.2006.05.055 BindingDB Entry DOI: 10.7270/Q2V987PC
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50188261 (2-(3-chloro-4-(5-methyl-4-((2-(4-(trifluoromethyl)...) Show SMILES Cc1onc(c1C(=O)NCCOc1ccc(cc1)C(F)(F)F)-c1ccc(CC(O)=O)cc1Cl Show InChI InChI=1S/C22H18ClF3N2O5/c1-12-19(20(28-33-12)16-7-2-13(10-17(16)23)11-18(29)30)21(31)27-8-9-32-15-5-3-14(4-6-15)22(24,25)26/h2-7,10H,8-9,11H2,1H3,(H,27,31)(H,29,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at PPARalpha by transactivation assay				Bioorg Med Chem Lett 16: 4376-80 (2006) Article DOI: 10.1016/j.bmcl.2006.05.055 BindingDB Entry DOI: 10.7270/Q2V987PC
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50188261 (2-(3-chloro-4-(5-methyl-4-((2-(4-(trifluoromethyl)...) Show SMILES Cc1onc(c1C(=O)NCCOc1ccc(cc1)C(F)(F)F)-c1ccc(CC(O)=O)cc1Cl Show InChI InChI=1S/C22H18ClF3N2O5/c1-12-19(20(28-33-12)16-7-2-13(10-17(16)23)11-18(29)30)21(31)27-8-9-32-15-5-3-14(4-6-15)22(24,25)26/h2-7,10H,8-9,11H2,1H3,(H,27,31)(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at PPARgamma by transactivation assay				Bioorg Med Chem Lett 16: 4376-80 (2006) Article DOI: 10.1016/j.bmcl.2006.05.055 BindingDB Entry DOI: 10.7270/Q2V987PC
					More data for this Ligand-Target Pair