BDBM50188263 2-(4-(5-tert-butyl-4-((2-(2,4-dichlorophenoxy)ethyl)carbamoyl)isoxazol-3-yl)-3-chlorophenyl)acetic acid::CHEMBL213876

SMILES: CC(C)(C)c1onc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccc(CC(O)=O)cc1Cl

InChI Key: InChIKey=VZGPQBGNXKUSIH-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50188263   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50188263 (2-(4-(5-tert-butyl-4-((2-(2,4-dichlorophenoxy)ethy...) Show SMILES CC(C)(C)c1onc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccc(CC(O)=O)cc1Cl Show InChI InChI=1S/C24H23Cl3N2O5/c1-24(2,3)22-20(23(32)28-8-9-33-18-7-5-14(25)12-17(18)27)21(29-34-22)15-6-4-13(10-16(15)26)11-19(30)31/h4-7,10,12H,8-9,11H2,1-3H3,(H,28,32)(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at PPARgamma by transactivation assay				Bioorg Med Chem Lett 16: 4376-80 (2006) Article DOI: 10.1016/j.bmcl.2006.05.055 BindingDB Entry DOI: 10.7270/Q2V987PC
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50188263 (2-(4-(5-tert-butyl-4-((2-(2,4-dichlorophenoxy)ethy...) Show SMILES CC(C)(C)c1onc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccc(CC(O)=O)cc1Cl Show InChI InChI=1S/C24H23Cl3N2O5/c1-24(2,3)22-20(23(32)28-8-9-33-18-7-5-14(25)12-17(18)27)21(29-34-22)15-6-4-13(10-16(15)26)11-19(30)31/h4-7,10,12H,8-9,11H2,1-3H3,(H,28,32)(H,30,31)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at PPARalpha by transactivation assay				Bioorg Med Chem Lett 16: 4376-80 (2006) Article DOI: 10.1016/j.bmcl.2006.05.055 BindingDB Entry DOI: 10.7270/Q2V987PC
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50188263 (2-(4-(5-tert-butyl-4-((2-(2,4-dichlorophenoxy)ethy...) Show SMILES CC(C)(C)c1onc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccc(CC(O)=O)cc1Cl Show InChI InChI=1S/C24H23Cl3N2O5/c1-24(2,3)22-20(23(32)28-8-9-33-18-7-5-14(25)12-17(18)27)21(29-34-22)15-6-4-13(10-16(15)26)11-19(30)31/h4-7,10,12H,8-9,11H2,1-3H3,(H,28,32)(H,30,31)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.59E+3	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at PPARdelta by transactivation assay				Bioorg Med Chem Lett 16: 4376-80 (2006) Article DOI: 10.1016/j.bmcl.2006.05.055 BindingDB Entry DOI: 10.7270/Q2V987PC
					More data for this Ligand-Target Pair