BDBM50188290 7-((4-methylpiperazin-1-yl)methyl)-3-phenyl-1,4-dihydroindeno[1,2-c]pyrazole::CHEMBL427050

SMILES: CN1CCN(Cc2ccc3Cc4c([nH]nc4-c4ccccc4)-c3c2)CC1

InChI Key: InChIKey=OEXUKNPIWNAZQT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50188290   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188290 (7-((4-methylpiperazin-1-yl)methyl)-3-phenyl-1,4-di...) Show SMILES CN1CCN(Cc2ccc3Cc4c([nH]nc4-c4ccccc4)-c3c2)CC1 Show InChI InChI=1S/C22H24N4/c1-25-9-11-26(12-10-25)15-16-7-8-18-14-20-21(17-5-3-2-4-6-17)23-24-22(20)19(18)13-16/h2-8,13H,9-12,14-15H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair